Hello Friends , here is the next video in the learning pharmacy series....
In this video , we have discussed about ROUTES OF ADMINISTRATION OF DRUGS. There are several routes my means of which the drug is administered or taken in the body. In this video , we discussed about ORAL ROUTE , BUCCAL & SUBLINGUAL ROUTE , INHALATION ROUTE AND TRANSDERMAL ROUTE along with the multiple choice questions which often asked in the competitive exams.Watch the complete video to get an idea about all the discussed routes.
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Topic discussed in the video :-
• Preferred by patients
• “Slow-release” preparations may be available to extend duration of action
• Drugs can be formulated in such a way as to protect them from digestive
enzymes, acid, etc.
Disadvantage-Unsuitable in patients who are uncooperative, strictly “nil by
mouth”, are vomiting profusely or have ileus
• Most orally administered drugs are absorbed slowly
• Unpredictable absorption due to degradation by stomach acid and
2-Buccal & Sublingual route - medication absorbs quickly, these types of administration can be important during emergencies when you need the drug to work right away, such as during a heart attack.
Further, these drugs do not go through the digestive system, so they aren’t metabolized through your liver. This means you may be able to take a lower dose and still get the same results.
Disadvantage-Eating, drinking, or smoking, can affect how the drug is absorbed and how well it works. Also, these forms don’t work for drugs that need to be processed slowly by your system, such as extended-release formulations. Any open sores in your mouth can also become irritated by the medication.
3-Inhalation route - Very rapid absorption due to the huge surface area of the respiratory endothelium
• Bronchodilators and inhaled steroids can be targeted to lungs
with low levels of systemic absorption
Disadvantage-• Bioavailability depends on patient’s inhaler technique and the size of drug particles generated by the delivery technique.
4-Transdermal route- This route involves the application of the patch to skin for systemic effect.Absorption occurs very slowly but the first pass metabolism is avoided. eg .. patches of nitroglycerine , fentanyl , Nicotine .
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Mera 1 question he plz answer me cefixim 200 mg din me 2 baar lena padta he par aajkal cefixim 400 mg aa gayi jo ki din me 1 baar lena padti he to dose kispar depend karta he t1/2 par ya kis karan par depend karta he plz answer
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